12/14/2023 0 Comments Frontal bone skull![]() ![]() ![]() Hypotheses suggested involve the role of leptin, a peptide that helps to control the metabolic rate. It is seen most commonly in older, post-menopausal females. ![]() HFI is characterized by benign overgrowth of the inner table of the frontal bone. Hyperostosis frontalis interna (HFI) has been reported in 5-12% of the general population, but is more commonly seen in women. Transaxial fused SPECT/CT images revealed irregular thickening and nodularity of the inner table of bilateral frontal and parietal bones showing increased tracer accumulation SPECT/CT of the cranium was done on Symbia T6 SPECT/ CT (Siemens). The importance of recognizing this entity on bone scans stems mainly from the necessity of not mistaking it for metastasis. Thus the heterogeneous pattern of Tc-99m Methylene diphosphonate uptake could be attributed to hyperostosis ruling out the possibility of sclerotic metastasis. The midline was spared and the external surface of the skull was unaffected, which is characteristic of hyperostosis fronto-parietalis. It revealed nodular and irregular thickening of the inner table of the frontal bone extending to involve the parietal bones. To characterize this lesion SPECT/CT of the cranium was carried out. The remaining skeleton showed normal tracer distribution. The planar bone scan revealed heterogeneously increased tracer uptake involving bilateral frontal and parietal bones. A 65-year post-menopausal female, treated case of right breast carcinoma had chest wall recurrence and was sent for bone scintigraphy to rule out skeletal involvement. ![]()
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